One of the most popular cannabis compounds is Tetrahydrocannabinol, also known as THC. Unlike the CBD, this is a mind-altering compound that gives psychoactive effects to its consumers in both marijuana and hemp.
CB2 receptors are located throughout the body, and most commonly found in the immune system. It was initially thought that CBD oil bound itself to these receptors, but now scientists believe that CBD oil works by influencing the body to use more of its own naturally-produced cannabinoids. Cannabidiol, or CBD, is another non-psychoactive cannabinoid with a wide scope of medical applications. Of the 85 known cannabinoids (the active ingredients in the cannabis plant), CBD and THC are usually present in the highest concentrations, and are therefore the most widely studied. From insomnia to nausea, cannabis can be used as a natural remedy for a multitude of ailments.
CBD is interesting in that it doesn’t directly act on either the CB1 or CB2 receptor. Instead, it acts on a variety of other cannabinoid receptors like TRPV-1, adenosine, and serotonin receptors to regulate the systems of the body. This sounds complex, but we’ll explain what each of these actions mean in practice. CBD can be an attractive option for many reasons, but it’s not as simple as just stopping your meds and dosing with CBD.
It’s not a direct translation, but that dosage would be somewhere in the range of several hundred milligrams for an adult human. Unlike with THC, CBD’s effects aren’t limited to that single receptor. These effects are not precisely known, though CBD certainly has some impact on CB1’s sister receptor (CB2) as well as a receptor called 5-HT1A. When the 5-HT1A receptor comes into contact with a material that agonizes it, the effects can include reduced anxiety and increased calmness.
CBD not only soothes difficult-to-treat pain in the short term, it’s also effective in the long term. For anyone who’s had to increase their opioid dose because they quickly develop a tolerance to it, this is big news! CBD allows patients to maintain their same dose for long periods of time, without the risk of addiction or dependence. Not only that, but there is a veritable mountain ofevidence to show that prolonged use of opioid pain relievers can cause addiction and dependence.
As CBD is extracted from plants and has been used medicinally for thousands of years, it stands to reason its properties should be explored further. Cannabinoids actively bind to special receptors on your cells and are part of what is known as your endocannabinoid system. This hemp extract oil is a huge network of cell receptor proteins that have a vast array of functions. Some receptors are found within your central nervous system, whereas others are found in other places, such as your reproductive organs, skin and digestive tract.
Delta-9-tetrahydrocannabinol, or THC, is probably the best-known thanks to its psychoactive properties — it’s the one that gets you "high" — but CBD is quickly gaining ground due to its potential therapeutic benefits. CBD is derived from a strain of the cannabis plant, but you can still take it on a plane. If you want to use marijuana therapeutically, you’ll reap the benefits of the aforementioned entourage effect.
It shows real promise in treating previously intractable disorders like schizophrenia, and without the destructive side effects of existing drugs. Blessing’s clinical manager contacts did not perform formal studies on CBD.
It is important to know that CBD doesn’t directly pair with receptors CB1 and CB2, which will help us understand whether or not CBD Oil will make you high. Between CBD and THC, THC is the one that causes one to be high. The difference in the chemical structures of the two cannabinoids is minimal, and it doesn’t explain the reason why one would be psychoactive while others are not. The way the two are received in the body is what makes all the difference.